Introduction

This leaflet tells you about St Mark’s Solution. Your doctor, stoma nurse, dietician or pharmacist can answer any questions.

What is St Mark’s Solution

St Mark’s solution is a salty and sweet drink. It helps your body take in water.
You can make it at home with cheap ingredients.

You may need this drink if you lose a lot of fluid from your stoma. If you lose more than 1½ litres a day, you may become dehydrated. This can make you feel unwell.

To stop this, you may need to drink 1 to 3 litres a day. You will be advised how much to take.
Sip it slowly through the day.

How to make the solution

Follow this recipe to make 1 litre:

Ingredient

Weight

Measures

Glucose powder

20g

SIX level 5ml spoonfuls

Table Salt (sodium chloride)

3.5g

ONE level 5ml spoonful

Baking soda (sodium bicarbonate)

2.5g

ONE heaped 2.5ml spoonful

Cold tap water

1 litre

 

Method

  1. Buy the powder ingredients from a supermarket or pharmacy. This is cheaper than getting them on prescription.
  2. Measure out the powders into a large jug or bowl.
  3. Add 1 litre of cold tap water.
  4. Stir until dissolved.
  5. Sip during the day.
  6. Throw away any left over after 24-hours.
  7. Prepare a fresh solution the following day.

If you need more than 1 litre a day

Some people need 2 or 3 litres of St Mark’s solution each day.
If this is you:

  • For 2 litres – use double the ingredients and 2 litres of water.
  • For 3 litres – use triple the ingredients and 3 litres of water.

Always sip slowly through the day.

Drinking the solution

You may find the solution tastes salty. You can improve this by:

  • Storing the drink in the fridge and drinking it chilled.
  • You can also freeze it and drink as a slush
  • Sipping it through a straw
  • Adding a small amount of squash, fruit juice or cordial. This is best added while making up the solution.
  • Adding fresh lemon or lime juice

Contact us

If you have any queries relating to this information, please contact the Pharmacy service.

About this information

Service:
Pharmacy

Reference:
S/020

Approval date:
30 September 2025

Review date:
9 January 2028

Click ‘show accessibility tools’ at the bottom of the page 

Accesibility tools snip.PNG

Then click ‘select language’  

dropdown menu reading 'Select language'

 


Interpreters for your appointment

Alternative formats 

You can use the accessibility toolbar at the bottom of your screen to: 

  • Change the text size 

  • Adjust the font 

  • Modify the colour contrast 

  • Use the translate function 

If you would like this information in another format, such as Braille, audio, or easy read, please speak to a member of staff. 

You can also print as well as download as PDF using the “Print this page” button at the end of the page.  

Staff will print a copy for you on request 

Important note 

This page provides general information only. It is developed by clinical staff and is reviewed regularly every 3 years for accuracy. For personal advice about your health, or if you have any concerns, please speak to your doctor.