Overview

The GTN spray is used to relieve angina pain and related symptoms. These can include referred pain/discomfort radiating down either left or right arm, to the jaw, neck, shoulders or back and may include shortness of breath. 

It can also be used to prevent an attack of angina occurring. It can be used prior to activities from which you may expect to get pain with, for example, climbing stairs, intercourse (not recommended if using drugs for erectile dysfunction such as Viagra) or walking up a steep hill. However it is not advisable to do this without specific instructions from your doctor or nurse.

How does GTN spray work?

The spray is applied under the tongue allowing the drug to be absorbed rapidly into the bloodstream. The active drug, glyceryl trinitrate, opens up many of the body’s veins and arteries, allowing the blood to flow faster and more freely, improving the oxygen supply to the heart.

How to use GTN spray

  • If possible sit down before using your spray
  • Take off the cap and hold the bottle upright
  • Hold your breath for a moment to avoid breathing in the spray, then open your mouth and spray a dose under your tongue
  • Use 1 or 2 sprays (never more than 3 at any one time), then close your mouth immediately and breathe normally

Carry this medication with you at all times

Keep it out of the sunlight and store in a cool place. Always check you have enough of the spray in the canister, especially before going off on holiday. Remember to check the expiry date. You can buy GTN spray over the counter in the Chemist.

The main side effects of the spray are headaches, flushing, redness of the skin and dizziness. These are usually only temporary and disappear after a few minutes. If however any of these effects are troublesome and you are unable to carry out your normal activities then contact your Doctor. Do try to persevere with the spray when you first start to use it.

Do not drive whilst experiencing angina pain. Ensure the pain has gone before you resume your normal activities. 

If you are increasingly using your spray on a daily basis it is advisable that you talk to your GP about this, as you may need a change of your medications in order to prevent the episodes of angina. Your GP will also need to know if the pain continues or returns during exercise or while you are resting. If you feel your condition is deteriorating at any time then please call for an ambulance.

CHEST PAIN INSTRUCTIONS

At the onset of pain, rest for 1-2 minutes If pain persists, take GTN tablet/spray

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If unrelieved after 5 minutes take further GTN tablet/spray

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If chest pain continues for a further 5 minutes take another GTN tablet/spray

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If you have chest pain despite taking 3 doses of GTN

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CALL 999 IMMEDIATELY

It is recommended you do not phone your GP first as this delays any emergency treatment you may require.
Do not wait more than 10 minutes for the pain to go without seeking medical attention.

If in doubt don’t wait, phone 999 for an ambulance.

Contact us

If you have any queries relating to this information, please contact the Cardiology service.

About this information

Service:
Cardiology

Reference:
C/039

Approval date:
9 January 2025

Review date:
9 January 2028

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Important note 

This page provides general information only. It is developed by clinical staff and is reviewed regularly every 3 years for accuracy. For personal advice about your health, or if you have any concerns, please speak to your doctor.